Aurel Popa-Wagner. Chapter IV - Alzheimer’s disease pathological factors in ischemic aged brain; in Ischemia-Reperfusion Pathways in Alzheimer's Disease. pp. 51-84., Dept. of Neurology, Univ. of Greifswald, Greifswald, Germany. Ed. R. Pluta, NOVA Publishers, 2007. ISBN: 978-1-60021-744-9
Aurel Popa-Wagner, Daniel Pirici, Laurentiu Mogoanta, Thomas Stanley Carmichael, Vincent Di Napoli and Charles Rosen. Regeneration of tissue and function after cerebral ischemia in the aged rats: New therapeutic strategies. In: Recent Advances and New Strategies in Stroke Research, Editor: Franciska Erdö, 2008, ISBN: 978-81-7895-385-4
Aurel Popa-Wagner, Adrian Balseanu, Leon Zagrean, Imtiaz M. Shah, Mario Di Napoli, Zaal Kokaia and Henrik Ahlenius. Editor. Kenneth Maiese Chapter 17: Neurobiology of Post-Ischemic Recuperation in the Aged Mammalian Brain. In: Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging. Oxford University Pres. 2008. ISBN: 978-0-19-532669-7
Popa-Wagner A, Pirici D, Petcu EP, Mogoanta A, Ana-Maria Buga, Rosen, CL, Leon R and Jason D. Huber. Chapter I. Cerebral Circulation: Anatomy, Distribution and Physiopathology. In Advances in Medicine and Biology. Vol. 8, pp. 1-45. Ed. Leon V. Berhardt. NOVA Publishers, 2010. ISBN: 978-1-61728-009-2
Ryszard Pluta, Aurel Popa-Wagner. Chapter 3. Ischemic stroke and cognitive impairment.
Mario Di Napoli, Craig J. Smith, Stephen J. Hopkins, Aurel Popa-Wagner, Ana Maria Buga, and Mark Slevin (2014) Neuroinflammation and Immune Regulation in Ischemic Stroke: Identification of New Pharmacological Targets. In Neuroinflammation and Neurodegeneration. Drs. P.K. Peterson and M. Torborek (Eds). Springer York. DOI 10.1007/978-1-4939-1071-7_11.Print ISBN: 978-1-4939-1070-0. Print online: 978-1-4939-1071-7
Ana-Maria Buga, Madalina Filfan, Badescu M. George and Aurel Popa-Wagner. The Impact of Aging on Post-Stroke Depression, in Depression: A Silent Culprit in Health and Disease, 2015, 51-67. Puneetpal Singh and Sarabjit Mastana (Eds). 2015 Bentham Science Publishers. DOI: 10.2174/97816810814581150101 eISBN: 978-1-68108-145-8; ISBN: 978-1-68108-146-5, 2015.
Aurel Popa-Wagner, Raluca Elena Sandu, Ovidiu Ciobanu. Co-transplantation Strategies and Combination Therapies for Stroke. In, K. Jin et al. (eds.), Bone marrow stem cell therapy for stroke,
Aurel Popa-Wagner, Danut-Adrian Dumbrava, Roxana Surugiu, Eugen Petcu, Daniela-Gabriela Glavan, Denissa-Greta Olaru, Raluca Sandu Elena. Therapeutic Options to Enhance Post-Stroke Recovery in Aged Humans. In Shamim I Ahmad (ed). AGING. Exploring a Complex Phenomenon. CRC Press (Taylor & Francis Group). ISBN 978-1-138-19697-1.
Aurel Popa-Wagner & Mario Di Napoli. Stem Cell Transplants in the Aged Stroke Brain: Microenvironment Factors. In, Cellular and Molecular Approaches to Regeneration and Repair (pp.47-71). Paul A. Lapchak, John H. Zhang (eds) Springer, DOI: 10.1007/978-3-319-66679-2_3. Print ISBN: 978-3-319-66678-5. Online ISBN: 978-3-319-66679-2. Print ISSN: 2363-958X
Daniela Glavan, Aurel Popa-Wagner. Aging, Circadian Rhythms and Molecular Psychiatry. Academica Greifswald, 2019. 978-3-940237-23-1
Wagner AP, L.P. Wagner, and M.C. Iordachel (1981). The purification and properties of a RNAse of the roe of the fish Cyprinus carpio. Comp. Biochem. Physiol.B 70, 147-152. IF 1.65
Wagner AP, M.C. Iordachel and L.P. Wagner (1982). A simple spectrophotometric method for the measurement of the RNAse activity in biological fluids. J.Biochem.Biophys.Methods 8, 291-298. IF 1.338
Wagner AP, L.P. Wagner and E. Psarrou (1982). Age-related changes in 28S RNA and 18S RNA in antigen stimulated and nonstimulated rat spleens. AGE 5, 113-118. IF 2.925
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Wagner AP, E.Psarrou and L.P. Wagner (1982). Age changes of the isoelectric points of nonhistone chromosomal proteins from rat liver in the pH range 5-8. Exp.Gerontol. 17, 359-364. IF 2.879
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Wagner AP, E. Psarrou and L.P. Wagner (1983). Age changes of isoelectric points of the molecular forms of tyrosine aminotransferase from rat liver. Gerontology 29, 299-304. IF 1.658
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Wagner AP and L.P. Wagner (1983). Concentration and analysis of proteins by a discontinuous pH gradient formed by isoelectric focusing in polyacrylamide gel. Int. J. Biochem. Cell Biology 15, 1463-1468. IF 4.0
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Wagner AP, M.C. Iordachel and L.P. Wagner (1983). Age changes in the H1 group of histones from rat liver. Exp.Gerontol. 17, 173-178. IF 2.879
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Wagner AP, E.Psarrou and L.P. Wagner (1983).Single step,rapid separation of acidic and basic isoenzymes from commercial horseradish peroxidase. Anal.Biochem. 129, 326-328. IF 3.002
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Wagner AP, E. Psarrou and L.P. Wagner (1984). Electrophoretic concentration of proteins in a nonlinear pH gradient. Anal.Biochem. 129, 326-328. IF 3.002
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Popa-Wagner, A. (1989). On the relationships between the rate of cytoskeletal stable assemblies turnover, stability of the differentiated state, development and aging.
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Popa-Wagner, A. (1990). On the strategy of directed assembly and its relevance to ageing. Gerontology 36, 132-139. IF 1.358
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Popa-Wagner, A. and Retey, J.(1990). Assay of N-myristoyl transferase by selective adsorption of myristoyl-CoA on acidic alumina. Analyt. Biochem. 188, 356-358. IF 3.002
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Popa-Wagner, A.and Retey, J.(1990). Synthesis of Myristoyl-carba(dethia)-CoA and S-[3-oxohexadecyl]- CoA, two potent inhibitors of N-Myristoyl Transferase. Eur.J.Biochem. 195, 699-705.
Popa-Wagner, A., G.Reck, and K.D.Beck (1991) Evidence that the V Sequence-Containing Form of Fibronectin mRNA is Increased in the Hippocampus of Aged Rats. NeuroReport 2, 691-694. IF 2.163
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Popa-Wagner, A., Day, R.D., Platt, D. and Pasinetti, G.M. (1992) Dopaminergic and astrocytic responses in striatum to cortical deafferentation (II). Decortication and striatal mRNA: Increases of mRNA for fibronectin, but not of NCAM or alpha-tubulin mRNA. NeuroReport 3, 853-856. IF 2.163
Popa-Wagner, A., K.D. Beck, and G.Reck (1992) N-CAM and N-Cadherin in Development and Aging: Selective Reduction in the 7.4-kb and 6.7-kb NCAM Messages in the Hippocampus of Adult and Old Rats. Mech. Ageing Dev. 62, 201-208. IF 4.308
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Popa-Wagner, A., G. Reck and D. Platt (1992) Dynamics of Gene Expression for Microtubule-Associated Protein MAP1B, Embryonic -Tubulin and Late Neural ß-Tubulin in the Hippocampus of Aged Rats. Biochem. Biophys. Res. Commun. 184, 292-299. IF 2.749
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Popa-Wagner, A., G. Reck and D. Platt (1993) Evidence that V+ Fibronectin, GFAP and S100ß mRNAs are Increased in the Hippocampus of Aged Rats. Exp. Gerontol. 28, 135-143. IF 2.879
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Dorner, H., Fischer, B., Platt, D., and Popa-Wagner, A. (1995) Evidence that fibronectin mRNA (FN-V+) is increased in the liver of old Sprague-Dawley rats. Opposing effect of food restriction. J. Gerontol., 150, B128-132. IF 2.932
Fischer, B. Schmoll, H., Riederer, P., Bauer, J., Platt, D. and Popa-Wagner, A. (1995) Complement C1q and C3 mRNA Expression in the Frontal Cortex of Alzheimer's Patients. J. Molec. Med. 73: 465-471. IF 4.8
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Fischer, B., Retchkiman, I., Bauer, J., Platt, D., and Popa-Wagner, A. (1995) Pentylenetetrazole-Induced Seizure Upregulates Levels of Microtubule-Associated Protein 1B mRNA and Protein in the Hippocampus of Rat. J. Neurochem. 65, 467-471. IF 4.451
Retchkiman, I., Fischer, B., Platt, D., and Popa-Wagner, A. (1996) Seizure induced c-fos mRNA in the rat brain: comparison between young and aging animals. Neurobiol. Aging 17: 41-44. IF 5.607
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Dorner, H., Fischer, B., Kessler, C., Platt, D., and Popa-Wagner, A. (1996) V+ Fibronectin mRNA is increased in the brain of aged rats: Effect of food restriction. Brain Res. 726:198-206 IF 2.218
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Fischer, B. and A. Popa-Wagner (1997) Synaptic plasticity is preserved in the temporal cortex of 20-mo-old rats. Arch. Gerontol. Geriatrics 25: 27-39. IF 1.289
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Popa-Wagner A, Fischer B, Schmoll H, Platt D, Kessler C (1997) Increased Expression of Microtubule-Associated Protein 1B in the Hippocampus, Subiculum, and Perforant Path of Rats Treated with a High Dose of Pentylenetetrazole. Exp. Neurol . 148: 73-82, 1997. IF 3.982
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A. Popa Wagner, B. Fischer, H. Schmoll, D. Platt and C. Kessler (1998) Altered Expression of Microtubule-Associated Protein 1B in Cerebral Cortical Structures of Pentylenetetrazole-Treated Rats. J. Neurosci. Res., 51: 646-657. IF 3.268
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A. Popa-Wagner, E. Schröder, L.C. Walker, Ch. Kessler (1998). ß-Amyloid Precursor Protein and Aß Peptide Immunoreactivity in the Rat Brain Following Middle Cerebral Artery Occlusion: Effect of Age. Stroke, 29: 2196-2202. IF 6.296
Popa-Wagner, A., E. Schröder, H. Schmoll1, L.C. Walker, and Ch. Kessler (1999) Upregulation of MAP1B and MAP2 in the Rat Brain Following Middle Cerebral Artery Occlusion: Effect of Age. J. Cereb. Blood Flow Met., 19: 425-434. IF 5.147
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Popa-Wagner, A., Fischer B, Schmoll H, Platt D, and Kessler, C. (1999) Anomalous Expression of Microtubule-Associated Protein 1B in the Hippocampus and Cortex of Aged Rats Treated with Pentylenetetrazole. Neuroscience, 94: 395-403. IF 7.5
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Popa Wagner, A., B. Fischer, D. Platt, H. Schmoll, and C. Kessler (2000) Delayed and blunted induction of the mRNA for tissue plasminogen activator in the brain of old rats following pentylenetetrazole-induced seizure activity. J. Gerontology, 55: B242-B248. IF 2.932
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Popa-Wagner, A., H.Schmoll, D. Platt, and C. Kessler (2000). Brain plasticity: to what extent do aged animals retain the capacity to coordinate gene activity in response to acute challenges. Exp. Gerontol. 35: 1211-1227. IF 2.879
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Schmoll H, Badan I, Fischer B, and A. Popa Wagner (2001) Dynamics of gene expression for immediate early- and late genes after seizure activity in aged rats. Arch. Gerontol. Geriatrics 32: 199-218. IF 1.289
Badan, I, D. Platt, Ch. Kessler, A. Popa-Wagner (2003).Temporal Dynamics of Degenerative and Regenerative Events Associated with Cerebral Ischemia in Aged Rats. Gerontology, 49: 356-365. IF 1.358
Badan I, Buchhold B, Walker L, Graz L, Kessler Ch, A. Popa-Wagner (2003). Accelerated glial reactivity to stroke in aged rats correlates with reduced functional activity. J. Cereb. Blood Flow Metab. 23: 845-854. DOI: 10.1097/01.WCB.0000071883.63724.A7. IF 5.147
Schroeder, E., S. Vogelgesang, A. Popa-Wagner, Ch. Kessler (2003). Neurofilament expression in the rat brain after cerebral infarction: effect of age. Neurobiol. Aging 24: 135-145. IF 5.607
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Schmoll, H., Badan, I., Walker, L., Kessler, Ch., and Popa-Wagner, A. (2003) Kindling status in Sprague-Dawley rats induced by pentylenetetrazole: involvement of a critical development period. Am. J. Pathol., 162: 1027-1034. IF 5.487
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Badan, I. Dinca, I, Buchhold, B, Suofu, Y, Walker, L, Kessler, Ch, Popa-Wagner, A (2004). Accelerated accumulation of N- and C-terminal βAPP fragments and delayed recovery of MAP1B expression following stroke in aged rats. Eur. J. Neurosci., 19: 2270-2280. IF 4.68
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Kuhr A, Popa-Wagner A, Schmoll H F, Schwahn C, Kocher T. (2004) Observations on experimental marginal periodontitis in rats. J Periodontal Res. 39:101-106. IF 2.146
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SSchmoll, H., S. Ramboiu, I.Badan, D. Platt, JG Herndon, Ch. Kessler and A. Popa-Wagner (2005) Age influences on the expression of GAP-43 in the rat hippocampus following seizure. Gerontology, 51: 215-224. IF 1.70
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Junkers, H., Späthe, K., Walther, R., Walker, L., Schwarz, G., Kramer, W., Nordheim, A. Kessler, Ch. and Popa-Wagner, A. (2005). Proteomic identification of a modified form of the Rieske iron-sulfur protein following seizure. Epilepsia, 46:339-343. IF 3.73
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A. Popa-Wagner, I. Dinca, S. Yalikun, L. Walker, H. Kroemer and Ch. Kessler. (2006) Accelerated delimitation of the infarct zone by capillary-derived nestin-positive cells in aged rats. Current Neurovascular Research 3, 3-13. IF 3.5
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P. Dazert, Y. Suofu, M. Grube, A. Popa-Wagner, H.K. Kroemer, G. Jedlitschky and C. Kessler (2006). Differential Regulation of Transport Proteins in the Periinfarct Region Following Reversible Middle Cerebral Artery Occlusion in Rats. Neuroscience 142: 1071-1079. IF 3.352
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Popa-Wagner A, Badan I, Walker L, Groppa S, Patrana N, Kessler, Ch (2007). Accelerated infarct development, cytogenesis and apoptosis following transient cerebral ischemia in aged rats. Acta Neuropathol. (Berlin), 113:277-293. IF 9.31
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Popa-Wagner, Carmichael, ST, Kokaia Z, and Walker, LC (2007) The response of the aged brain to stroke: Too much, too soon? Current Neurovascular Research 4:216-277. IF 3.5
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Buchhold, B, Mogoanta L, Suofu Y, Hamm A, Walker L, Kessler C, Popa-Wagner, A (2007) Environmental enrichment improves functional and neuropathological indices following stroke in young and aged rats. Restorative Neurol. Neurosci. 25: 1–18. IF 2.415
Junker H, Suofu Y, Venz S, Sascau S, Herndon JG, Kessler C, Walther R, and Popa-Wagner A (2007). Proteomic identification of an upregulated isoform of Annexin A3 in the rat brain following reversible cerebral ischemia. Glia, 55: 1630-1637. IF 5.4
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Petcu EB, Sfredel V, Platt D, Herndon JG, Kessler C, Popa-Wagner A (2008). Cellular and molecular events underlying the dysregulated response of the aged brain to stroke: a mini-review. Gerontology 54:6-17. IF 1.70
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Buga AM, Sascau M, Herndon JG, Kessler K and Popa-Wagner A (2008) The genomic response of the contralateral cortex to stroke is diminished in the aged rats. J. Cell. Mol. Med. 12: 2731-2753 IF 6.807
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Baltromejus F, Vintilescu R, Balseanu AT, Buga AM, Grisk O, Walker LC, Kessler C, and Popa-Wagner A (2008). Long-term hypothermia reduces infarct volume in aged rats after focal ischemia. Neurosci. Letters 438:180–185. IF 2.5
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Eugen Bogdan Petcu, Thomas Kocher, Alexander Kuhr, Ana-Maria Buga, James G. Herndon, Christof Kessler and Aurel Popa-Wagner (2008). Mild systemic inflammation has a neuroprotective effect after stroke in rats. Current Neurovascular Research, 5: 214-222. IF 3.25
Carapancea M, Alexandru O, Fetea AS, Dragutescu L, Castro J, Georgescu A, Popa-Wagner A, Bäcklund ML, Lewensohn R, Dricu A. (2009) Growth factor receptors signaling in glioblastoma cells: therapeutic implications. J Neurooncol. 92:137-47. IF 2.82
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Popa-Wagner, K. Stocker, A. Balseanu, A. Rogalewski, K. Diederich, J. Minnerup, C. Margaritescu, W.-R. Schabitz (2010) Effects of Granulocyte-Colony Stimulating Factor after stroke in aged rats. Stroke, 41:1027-1031. DOI: 10.1161/STROKEAHA.109.575621 (IF 6.49)
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M Moldovan, AO Constantinescu, A Balseanu, L Zagrean, A Popa-Wagner (2010) Sleep deprivation attenuates experimental stroke severity in rats. Exp. Neurology, 222:135-143. IF 4.28
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Popa-Wagner A, Pirici D, Petcu EP, Mogoanta A, Ana-Maria Buga, Rosen, CL, Leon R and Jason D. Huber. Pathophysiology of the Vascular Wall and its Relevance for Cerebrovascular Disorders in Aged Rodents. Curr. Neurovasc. Res. 7: 251-267, 2010. IF 3.25
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A. Popa-Wagner, A-M. Buga and Z. Kokaia (2011) Perturbed Cellular Response to Brain Injury During Aging. Aging Research Reviews, 10:71-9. IF = 6.5
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A-M Buga, R Vintilescu, O T Pop and A Popa–Wagner (2011) Brain Aging and Regeneration after Injuries: an Organismal approach. Aging and Disease, 2: 64-79.
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Di Napoli M, Godoy DA, Campi V, Del Valle M, Piñero G, Mirofsky M, Popa-Wagner A, Masotti L, Papa F, Rabinstein AA (2011). C-reactive protein level measurement improves mortality prediction when added to the spontaneous intracerebral hemorrhage score. Stroke 42:1230-1236. (IF 6.2)
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Anghel A, Taranu G, Seclaman E, Rata A, Tamas L, Moldovan H, Ursoniu S, Samoila C, Ionac M, and Popa-Wagner A (2011). Efficiency and safety of vascular endothelial and hepatocyte growth factors gene therapy in patients with critical limb ischemia. Curr. Neurovasc. Res. 8:183-9. IF 3.25
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Pluta R, Jolkkonen J, Cuzzocrea S, Pedata F, Cechetto D, Popa-Wagner A. Cognitive Impairment with Vascular Impairment and Degeneration. Curr Neurovasc Res. 8:342-50, 2011; IF 3.25
Di Napoli M, Elkind MS, Godoy DA, Singh P, Papa F, Popa-Wagner A. Role of C-reactive protein in cerebrovascular disease: a critical review. Expert Rev Cardiovasc Ther. 2011 9:1565-84.
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Popa-Wagner A, Buga AM, Turner RC, Rosen CL, Toescu E. Cerebrovascular disorders: role of aging. J Aging Res. 2012; 2012:128146.
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Loubinoux I, Kronenberg G, Endres M, Schumann-Bard P, Freret T, Filipkowski RK, Kaczmarek L, Popa-Wagner A. Poststroke depression: mechanisms, translation and therapy. J Cell Mol Med. 16:1961-9, 2012. IF 4.25
Joseph C, Buga AM, Vintilescu R, Balseanu AT, Moldovan M, Junker H, Walker L, Lotze M, Popa-Wagner A. Prolonged gaseous hypothermia prevents the upregulation of phagocytosis-specific protein Annexin 1 and causes low-amplitude EEG activity in the aged rat brain after cerebral ischemia. J Cereb Blood Flow Metab. 32:1632-42, 2012. DOI: 10.1038/jcbfm.2012.65 (IF 6.0)
A-M Buga, R Vintilescu, A T Balseanu, O T Pop, C Streba, E Toescu, A Popa-Wagner
Repeated PTZ treatment at 25-day intervals leads to a highly efficient accumulation of doublecortin in the dorsal hippocampus of rats. PLoS ONE, 7:e39302, 2012. (IF 4.54)
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M Di Napoli, D A Godoy, V Campi, L Masotti, C J Smith, A P-Jones, S J Hopkins, M Slevin, F Papa, L Mogoanta, D Pirici, and A Popa-Wagner. (2012) C-Reactive Protein After Intracerebral Hemorrhage. Time-course, Tissue Localization and Prognosis. Neurology, 79:690-699, 2012. DOI: 10.1212/WNL.0b013e318264e3be (IF 8.3)
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Ana Maria Buga, C Scholz, S Kumar, J G Herndon, D Alexandru, G R Cojocaru, T Dandekar,
A Popa-Wagner. Identification of new therapeutic targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after stroke. PLoS ONE, 7: e50985, 2012. (IF 4.54)
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Kirchhoff F, Debarbieux F, Kronland-Martinet C, Cojocaru GR, Popa-Wagner A. Combined two-photon laser-scanning microscopy and spectral microCT X-ray imaging to characterize the cellular signature and evolution of microstroke foci. Rom J Morphol Embryol. 53(3 Suppl): 671-5, 2012. (IF 1.0)
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Raza SS, Khan MM, Ahmad A, Ashafaq M, Islam F, Wagner AP, Safhi MM, Islam F (2013). Neuroprotective effect of naringenin is mediated through suppression of NF-κB signaling pathway in experimental stroke. Neuroscience. 230:157-71. Epub 2012 Oct 26. (IF = 3.4).
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Buga AM, Di Napoli M, Popa-Wagner A (2013). Preclinical models of stroke in aged animals with or without comorbidities: role of neuroinflammation. Biogerontology 14:651-62. doi: 10.1007/s10522-013-9465-0. (IF = 3,7)
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Hermann DM, Buga AM, Popa-Wagner A. (2013) Enabling brain plasticity and neurological recovery in the ischemic brain: effect of age and vascular risk factors as confounders. Rom J Morphol Embryol. 2013;54(3 Suppl):687-93. (IF = 1,0)
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Popa-Wagner A, Mitran S, Sivanesan S, Chang E, Buga AM (2013). ROS and brain diseases: the good, the bad, and the ugly. Oxid Med Cell Longev. 2013;2013:963520. doi: 10.1155/2013/963520. (IF = 4,8)
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A Popa-Wagner, K Furczyk, J Richter, G Irmisch and J Thome (2013). Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels. Journal of Molecular Psychiatry, 1:20 doi:10.1186/2049-9256-1-20.
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Cojocaru GR, Popa-Wagner A, Stanciulescu EC, Babadan L and Buga AM (2013). Post-stroke depression and the aging brain. Journal of Molecular Psychiatry, 1:14. doi:10.1186/2049-9256-1-14.
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Di Napoli M, Parry-Jones AR, Smith CJ, Hopkins SJ, Slevin M, Masotti L, Campi V, Singh P, Papa F, Popa-Wagner A, Tudorica V, Godoy DA. (2014) C-reactive protein predicts hematoma growth in intracerebral hemorrhage. Stroke. 45:59-65. doi: 10.1161/STROKEAHA.113.001721. (IF = 6,2)
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Buga AM, Margaritescu C, Scholz CJ, Radu E, Zelenak C, Popa-Wagner A. (2014) Transcriptomics of post-stroke angiogenesis in the aged brain. Front Aging Neurosci. 6:44. doi:10.3389/fnagi.2014.00044. (IF = 4,5) ISSN=1663-4365.
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Muresanu DF, Popa-Wagner A, Stan A, Buga AM, Popescu BO (2014). The vascular component of Alzheimer's disease. Curr Neurovasc Res. 11:168-76. (IF = 2,9)
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Tatarishvili, Oki K, Buga AM, Popa-Wagner A, Brüstle O, Lindvall O, Kokaia Z. (2014) Human induced pluripotent stem cells improve recovery in stroke-injured aged rats. Restor Neurol Neurosci. 2014 32(4):547-58. (IF = 4,9)
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Balseanu A, Buga AM, Wagner DC, Boltze J, Reymann K, Schaebitz W, and A Popa-Wagner (2014). Multimodal approaches for regenerative stroke therapies: Combination of G-CSF with BM MSC is not superior to G-CSF alone. Frontiers Aging Neurosci. Front Aging Neurosci. 6:130. doi: 10.3389/fnagi.2014.00130. eCollection 2014 (IF = 5,4)
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Popa-Wagner A, Buga AM, Tica AA, Albu CV (2014) Perfusion deficits, inflammation and aging precipitate depressive behaviour. Biogerontology 15:439-48. doi: 10.1007/s10522-014-9516-1. (IF = 3,4)
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Popa-Wagner A, Buga A-M, Doeppner TR and Hermann DM (2014) Stem cell therapies in preclinical models of stroke associated with aging. Front. Cell. Neurosci. 8:347. doi: 10.3389/fncel.2014.00347 (IF = 4.3)
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M Sanmarti, L Ibáñez, S Huertas, D Badenes, D Dalmau, M Slevin, J Krupinski, A Popa-Wagner and A Jaen (2014) HIV-associated neurocognitive disorders. Journal of Molecular Psychiatry 2014, 2:2 doi:10.1186/2049-9256-2-2
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M F-Stanculete, AM Buga, A Popa-Wagner and D Dumitrascu (2014). The relationship between irritable bowel syndrome and psychiatric disorders: from molecular changes to clinical manifestations. Journal of Molecular Psychiatry 2014, 2:4 doi:10.1186/2049-9256-2-4.
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Scheller A, Vivien D, Kirchhoff F, Orset C, Sandu RE, Popa-Wagner A. (2014) Imaging neuroinflammation after brain injuries by ultrasensitive MRI and two-photon laser-scanning microscopy. Rom J Morphol Embryol. 55:735-43. (IF = 0,80)
Gaman AM, Buga AM, Gaman MA, Popa-Wagner A (2014). The role of oxidative stress and the effects of antioxidants on the incidence of infectious complications of chronic lymphocytic leukemia. Oxid Med Cell Longev. 158135. doi: 10.1155/2014/158135. Epub 2014 Oct 14. (IF = 4,6)
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Sandu RE, Uzoni A, Coman C, Popa-Wagner A. Cerebral ischemia in the aged. Limited anti-inflammatory efficacy of the indomethacin treatment. Rom J Morphol Embryol. 56(3):1111-7. PubMed PMID: 26662147. (IF = 0.7)
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Manole E, Ceafalan LC, Oproiu AM, Popa-Wagner A, Popescu BO (2015). Claudin-1 and occludin expression in demyelinating peripheral neuropathies. Rom J Morphol Embryol. 56(3):1097-102. PubMed PMID: 26662145. (IF = 0.7)
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Popa-Wagner A, Filfan M, Uzoni A, Pourgolafshan P, Buga AM (2015). Poststroke Cell Therapy of the Aged Brain. Neural Plast. 839638. doi: 10.1155/2015/839638. Epub 2015 Aug 11. Review. PubMed PMID: 26347826; PubMed Central PMCID: PMC4548142. (IF = 3,6).
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Buga AM, Scheibe J, Moller K, Ciobanu O, Posel C, Boltze J, Popa-Wagner A. (2015) Granulocyte colony-stimulating factor and bone marrow mononuclear cells for stroke treatment in the aged brain. Curr Neurovasc Res. 2015;12(2):155-62. PubMed PMID: 25760217. (IF = 2.2).
Bucur O, Almasan A, Friedman M, Nicolson GL, Godwin AK, Adami HO, Richardson DR, Schmitt-Ulms G, Westerblad H, Keniry M, Grau GE, Carbonetto S, Popa-Wagner A, Baron BW, Galardy PJ, Yang F, Data D, Nelson MA, Liehn EA (2015). An updated h-index measures both the primary and total scientific output of a researcher. Discoveries 3(3). pii: e50. Epub 2015 Sep 30. PubMed PMID: 26504901; PubMed Central PMCID: PMC4617786.
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Popa-Wagner A, Buga AM, Dumitrascu DI, Uzoni A, Thome J, Coogan AN. How does healthy aging impact on the circadian clock? J Neural Transm (Vienna). 2015 Jul 15. [Epub ahead of print] PubMed PMID: 26175004. (IF = 2.7).
Freret T, Gaudreau P, Schumann-Bard P, Billard JM, Popa-Wagner A. Mechanisms underlying the neuroprotective effect of brain reserve against late life depression. J Neural Transm (Vienna). 2015 Aug;122 Suppl 1:S55-61. doi: 10.1007/s00702-013-1154-2. (IF = 2.7).
Hermann DM, Buga AM, Popa-Wagner A. (2015) Neurovascular remodeling in the aged ischemic brain. J Neural Transm (Vienna). 122 Suppl 1:S25-33. doi: 10.1007/s00702-013-1148-0. (IF = 2.7).
Popa-Wagner A, Buga AM, Popescu B, Muresanu D. Vascular cognitive impairment, dementia, aging and energy demand. A vicious cycle. J Neural Transm (Vienna). 2015 Aug;122 Suppl 1:S47-54. doi: 10.1007/s00702-013-1129-3. Epub 2013 Dec 14. PubMed PMID: 24337666. (IF = 2.4).
Sandu RE, Buga AM, Uzoni A, Petcu EB, Popa-Wagner A (2015). Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology. Neural Regen Res. 10(9):1349-55. doi: 10.4103/1673-5374.165208. Review. PubMed PMID: 26604877; (IF = 2.2).
Slevin M, Matou S, Zeinolabediny Y, Corpas R, Weston R, Liu D, Boras E, Di Napoli M, Petcu E, Sarroca S, Popa-Wagner A, Love S, Font MA, Potempa LA, Al-Baradie R, Sanfeliu C, Revilla S, Badimon L, Krupinski J (2015). Monomeric C-reactive protein--a key molecule driving development of Alzheimer's disease associated with brain ischaemia? Sci Rep. 5:13281. doi: 10.1038/srep13281. (IF = 5.6).
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Behrouz R, Azarpazhooh MR, Godoy DA, Hoffmann MW, Masotti L, Parry-Jones AR, Popa-Wagner A, Schreuder FH, Slevin MA, Smith CJ, Di Napoli M (2015). MNEMONICH Steering Committee. The Multi-National survey on Epidemiology, Morbidity, and Outcomes in Intracerebral Haemorrhage (MNEMONICH). Int J Stroke. 10:E86. doi: 10.1111/ijs.12629. PubMed PMID: 26745705. (IF = 3.8).
Sandu RE, Buga AM, Balseanu AT, Moldovan M, and Popa-Wagner A. (2016) Twenty four hours hypothermia has temporary efficacy in reducing brain infarction and inflammation in aged rats. Neurobiology of Aging, 38:127-140. DOI: 10.1016/j.neurobiolaging.2015.11.006.
(IF = 5.3).
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Coogan Andrew N, Baird Alison L, Popa-Wagner Aurel, Thome Johannes (2016). Circadian rhythms and attention deficit hyperactivity disorder: The what, the when and the why. Progress in Neuropsychopharmacol & Biol Psychiatry, doi: 10.1016/j.pnpbp.2016.01.006 (IF = 3.7).
Di Napoli M, Zha AM, Godoy DA, Masotti L, Schreuder FH, Popa-Wagner A, Behrouz R (2016); from the MNEMONICH Registry. Prior Cannabis Use Is Associated with Outcome after Intracerebral Hemorrhage. Cerebrovasc Dis. 41(5-6):248-255. (IF = 3.75).
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Sandu RE, Uzoni A, Moldovan M, Ciobanu O, Anghel A, Radu E, Coogan AN, and Popa-Wagner A. (2016) Post-stroke gaseous hypothermia increases vascular density but not neurogenesis in the ischemic penumbra of aged rats. Rest. Neurol. Neurosci. 24;34(3):401-14. doi: 10.3233/RNN-150600. (IF = 4.7).
Buga AM, Ciobanu O, Sandu RE, Catalin Bogdan, Weston R, Slevin M, DiNapoli M, Popa-Wagner A (2016) Up-regulation of serotonin receptor 2B mRNA and protein in the peri-infarcted area of aged rats and stroke patients. Oncotarget, doi: 10.18632/oncotarget.8277. (IF = 6.4).
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Eugen B Petcu, K. Sherwood, A. Popa-Wagner, AM Buga, L. Aceti, Rodica I Miroiu. Artistic skills recovery and compensation in visual artists after stroke (2016). Frontiers Neurology, :76. doi: 10.3389/fneur.2016.00076. eCollection 2016. (IF = 3.1).
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Gaman AM, Uzoni A, Popa-Wagner A, Andrei A, Petcu EB. (2016). The Role of Oxidative Stress in Etiopathogenesis of Chemotherapy Induced Cognitive Impairment (CICI)-"Chemobrain". Aging Dis. 2016 May 27;7(3):307-17. doi: 10.14336/AD.2015.1022. eCollection 2016. (IF = 5.4).
Popa-Wagner A, AM Buga (2016) Identification of New Therapeutic Targets for Cerebral Ischemia by Genome-Wide Analysis. Biochem Anal Biochem, 5:e162. (IF = 2.4).
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Popa-Wagner A. The Role of Circadian Rhythms in Aging and ADHD (2016)
Fortschr Neurol Psychiatr. 84(S 02):S77-S79. Epub 2016 Nov 2. (IF = 0.36)
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Sandu RE, Balseanu A, Bogdan C, Slevin M, Petcu E, Popa-Wagner A. (2017) Stem cell therapies in preclinical models of stroke. Is the aged brain microenvironment refractory to cell therapy? Exp Gerontol. pii: S0531-5565(17)30029-3. doi: 10.1016/j.exger.2017.01.008. (IF = 3.6)
External link:
Behrouz R, Misra V, Godoy DA, Topel CH, Masotti L, Klijn CJ, Smith CJ, Parry-Jones AR, Slevin MA, Silver B, Willey JZ, Masjuán Vallejo J, Nzwalo H, Popa-Wagner A, Malek AR, Hafeez S, Di Napoli M. Clinical Course and Outcomes of Small Supratentorial Intracerebral Hematomas (2017). J Stroke Cerebrovasc Dis. pii: S1052-3057(17)30024-1. doi: 1016/j.jstrokecerebrovasdis.2017.01.010. (IF = 3.0)
Di Napoli M, Behrouz R, Topel CH, Misra V, Pomero F, Giraudo A, Pennati P, Masotti L, Schreuder FHBM, Staals J, Klijn CJM, Smith CJ, Parry-Jones AR, Slevin MA, Silver B, Willey JZ, Azarpazhooh MR, Vallejo JM, Nzwalo H, Popa-Wagner A, Godoy DA. (2017) Hypoalbuminemia, systemic inflammatory response syndrome, and functional outcome in intracerebral hemorrhage. J Crit Care. 2017 Jun 1;41:247-253. doi: 0.1016/j.jcrc.2017.06.002.
Ciobanu O, Sandu RE, Balseanu AT, Zavaleanu A, Gresita A, Petcu EB, Uzoni A, and Popa-Wagner A. (2017) Caloric restriction stabilizes body weight and accelerates behavioural recovery in aged rats after focal ischemia. Aging Cell, 2017, 16(6):1394-1403. doi: 10.1111/acel.12678. (IF = 6.7).
Popa-Wagner A, Glavan DG, Olaru A, Olaru DG, Margaritescu O, Tica O, Surugiu R, Sandu RE. (2018) Present Status and Future Challenges of New Therapeutic Targets in Preclinical Models of Stroke in Aged Animals with/without Comorbidities. Int J Mol Sci. 19(2). pii: E356. doi: 10.3390/ijms19020356. PMID: 29370078. ISSN: 1422-0067 (IF = 3.8)
Popa-Wagner A, Sandu RE, Cristin C, Uzoni A, Welle KA, Hryhorenko JR, Ghaemmaghami S. (2018) Increased Degradation Rates in the Components of the Mitochondrial Oxidative
Phosphorylation Chain in the Cerebellum of Old Mice. Front Aging Neurosci. 10:32. doi: 10.3389/fnagi.2018.00032. eCollection 2018. (IF = 4.6)
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Petcu EB, Midha R, McColl E, Popa-Wagner A, Chirila TV, Dalton PD. (2018) 3D printing strategies for peripheral nerve regeneration. Biofabrication. 10(3):032001. doi: 10.1088/1758-5090/aaaf50. (IF = 6.83)
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Syed Shadab Raza, Wagner AP, Yawer S. Hussain and Mohsin Ali Khan (2018). Mechanisms underlying dental-derived stem cell-mediated neurorestoration in neurodegenerative disorders. Stem Cell Research & Therapy 9:245. doi.org/10.1186/s13287-018-1005-z. PMID: 30257724 ISSN:2637-9589. (IF = 5.3).
Di Napoli M, Slevin M, Popa-Wagner A, Singh P, Lattanzi, Divani AA. (2018) Monomeric C-Reactive Protein and Cerebral Hemorrhage: From Bench to Bedside. Front Immunol. 2018 9:1921. doi: 10.3389/fimmu.2018.01921. eCollection 2018. (IF=6.5)
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Mundugaru R, Sivanesan S, Popa-Wagner A, Udaykumar P, Kirubagaran
R, Kp G, Vidyadhara DJ. (2018) Pluchea lanceolata protects hippocampal neurons from endothelin-1 induced-ischemic injury to ameliorate cognitive deficits. J Chem Neuroanat. 94:75-85. doi: 10.1016/j.jchemneu.2018.09.002. PMID: 30273663. (IF=2.1).
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Zagrean A-M, Hermann DM, Opris I, Zagrean L and Popa-Wagner A (2018) Multicellular Crosstalk Between Exosomes and the Neurovascular Unit After Cerebral Ischemia. Therapeutic Implications. Front. Neurosci. 12:811. doi: 10.3389/fnins.2018.00811 (IF=3.5) ISSN: 1664-3224.
R Surugiu, G Daniela, M Popescu, O Margaritescu, R Eugen, A Popa-Wagner (2018). Vasculature remodelling in a rat model of cerebral ischemia. The fate of the BrdU-labelled cells prior to stroke. Front. Neurol. 9:1014. doi: 10.3389/fneur.2018.01014 (IF=3.5)
ISSN: 1664-2295.
External link:
Al-Shahi Salman R, Frantzias J, Lee RJ, Lyden PD, Battey TWK, Ayres AM, Goldstein JN,…Popa-Wagner A. (2018) Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data. Lancet Neurol. 17(10):885-894. doi: 10.1016/S1474-4422(18)30253-9. (IF=28)
Hermann DM, Popa-Wagner A, Kleinschnitz C, Doeppner TR. (2019) Animal models of ischemic stroke and their impact on drug discovery. Expert Opin Drug Discov. 14(3):315-326. doi: 10.1080/17460441.2019.1573984. (IF =4,4). PMID: 30714423. (ISSN 1746-0441 [print], 1746-045X [ electronic]). RIS=1,57
Popa-Wagner A, Hermann D, Gresita A. (2019) Genetic conversion of proliferative
astroglia into neurons after cerebral ischemia: a new therapeutic tool for the
aged brain? Geroscience. 41:363–368. doi: 10.1007/s11357-019-00084-0. [Epub
ahead of print] Review. PMID: 31300928. IF=6.2; ISSN: 0161-9152 (print); 1574-4647 (web)
External link:
Manrique-Castano D, Sardari M, Silva de Carvalho T, Doeppner TR, Popa-Wagner A, Kleinschnitz C, Chan A, Hermann DM (2019) Deactivation of ATP-Binding Cassette Transporters ABCB1 and ABCC1 Does Not Influence Post-ischemic Neurological Deficits, Secondary Neurodegeneration and Neurogenesis, but Induces Subtle Microglial Morphological Changes. Front Cell Neurosci. 13:412. doi:10.3389/fncel.2019.00412. eCollection 2019. PMID: 31572128. IF=4.6; RIS=1.5; ISSN: 1662-5102
External link:
Dirk M. Hermann, Thorsten R. Doeppner, and Aurel Popa-Wagner (2019) Opportunities and Limitations of Vascular Risk Factor Models in Studying Plasticity-Promoting and Restorative Ischemic Stroke Therapies, Neural Plasticity, vol. 2019, Article ID 9785476, https://doi.org/10.1155/2019/9785476. IF=3.5; RIS=1.6. ISSN 2090-5904
External link:
Roxana Surugiu, Andrei Olaru, Dirk Hermann, Daniela Glavan, Bogdan Catalin, Aurel Popa-Wagner (2019) Recent advances in mono- and combined stem cell therapies of stroke in animal models and humans. Int J Mol Sci 20:6029 doi.org/10.3390/ijms20236029. ID= ijms-645511; IF=4. 3; ISSN 1422-0067
External link:
Gresita A, Glavan DG, Udristoiu I, Hermann DM, Popa-Wagner, A (2019)
Very low efficiency of direct reprogramming of astrocytes intro neurons in the brains of young and aged mice after cerebral ischemia. Frontiers in Aging Neuroscience, 11:334. doi: 10.3389/fnagi.2019.00334. IF =4,5
External link:
Roxana Surugiu, Bogdan Catalin, Danut Dumbrava, Andrei Gresita, Denisa Greta Olaru, Dirk M Hermann, Aurel Popa-Wagner (2019). Intracortical Administration of the Complement C3 Receptor Antagonist Trifluoroacetate Modulates Microglia Reaction after Brain Injury
Neural Plasticity 2019, ID 1071036, https://doi.org/10.1155/2019/1071036; IF =3,5
External link:
Popa-Wagner A, Dumitrascu DI, Capitanescu B, Petcu EB, Surugiu R, Fang WH,
Dumbrava DA. (2020) Dietary habits, lifestyle factors and neurodegenerative diseases.
Neural Regen Res. 15(3):394-400. doi:10.4103/1673-5374.266045. Review.
PMID: 31571647; IF=2,5. ISSN Web 1876-7958. ISSN print: 1673-5374. RIS =0.116; IF =3,1
External link:
Paudyal, A, Ghinea, FS, Driga, MP, Wen-Hui Fang, Alessandri Giulio, Combes L, Degens H, Slevin M, Hermann DM, Popa-Wagner A (2020) p5 Peptide-Loaded Human Adipose-Derived Mesenchymal Stem Cells Promote Neurological Recovery After Focal Cerebral Ischemia in a Rat Model. Transl. Stroke Res. https://doi.org/10.1007/s12975-020-00805-0. IF =5,8
Chen Wang, Verena Börger, Maryam Sardari, Florian Murke, Jelena Skuljec, Refik Pul, Nina Hagemann, Egor Dzyubenko, Robin Dittrich, Jonas Gregorius, Mike Hasenberg, Christoph Kleinschnitz, Aurel Popa-Wagner, Thorsten R Doeppner, Matthias Gunzer, Bernd Giebel, Dirk M Hermann (2020) Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically Neutrophils [published online ahead of print, 2020 Apr 21]. Stroke. 2020;STROKEAHA119028012. IF =6,5
Eugen B Petcu, Christopher Andry, Eric J Burks, Stephen Hamlet, Emiel AM Janssen, Kjell H Kjellevold, Antonio de Las Morenas, Nancy S Miller, Rodica I Miroiu, Iulian Nusem, Aurel Popa-Wagner. The SARS-CoV2 - ACE2 link: a physiopathological analysis. Vascular Cell, [S.l.], v. 12, n. 1, p. 5, aug. 2020. ISSN 2045-824X.
External link:
Paudyal A, Ghinea FS, Driga MP, Fang WH, Alessandri G, Combes L, Degens H, Slevin M, Hermann DM, Popa-Wagner A. p5 Peptide-Loaded Human Adipose-Derived Mesenchymal Stem Cells Promote Neurological Recovery After Focal Cerebral Ischemia in a Rat Model. Transl Stroke Res. 2020 May 6. doi: 10.1007/s12975-020-00805-0. Epub ahead of print. PMID: 32378028.
Stănescu I, Bulboacă AE, Micu IC, Bolboacă SD, Feștilă DG, Bulboacă AC, Bodizs G, Dogaru G, Boarescu PM, *Popa-Wagner A, Roman A. Gender Differences in the Levels of Periodontal Destruction, Behavioral Risk Factors and Systemic Oxidative Stress in Ischemic Stroke Patients: A Cohort Pilot Study. J Clin Med. 2020 Jun 4;9(6):1744. doi: 10.3390/jcm9061744. PMID: 32512870; PMCID: PMC7356570. *Corresponding author
Popa-Wagner A, Petcu EB, Capitanescu B, Hermann DM, Radu E, Gresita A. Ageing as a risk factor for cerebral ischemia: Underlying mechanisms and therapy in animal models and in the clinic. Mech Ageing Dev. 2020 Sep;190:111312. doi: 10.1016/j.mad.2020.111312. Epub 2020 Jul 11. PMID: 32663480.
Balseanu AT, Grigore M, Pinosanu LR, Slevin M, Hermann DM, Glavan D, Popa-Wagner A. Electric Stimulation of Neurogenesis Improves Behavioral Recovery After Focal Ischemia in Aged Rats. Front Neurosci. 2020 Jul 9;14:732. doi: 10.3389/fnins.2020.00732. PMID: 32742258; PMCID: PMC7365235.
External link:
Slevin M, E EG, Capitanescu B, Sanfeliu C, Zeinolabediny Y, AlBaradie R, Olah P, Guo B, Pirici D, Napoli MD, Popa-Wagner A. Monomeric C-Reactive Protein Aggravates Secondary Degeneration after Intracerebral Haemorrhagic Stroke and May Function as a Sensor for Systemic Inflammation. J Clin Med. 2020 Sep 22;9(9):E3053. doi: 10.3390/jcm9093053. PMID: 32971821.
External link:
Sardari M, Skuljec J, Yin D, Zec K, de Carvalho TS, Albers D, Wang C, Pul R, Popa-Wagner A, Doeppner TR, Kleinschnitz C, Dzyubenko E, Hermann DM. Lipopolysaccharide-induced sepsis-like state compromises post-ischemic neurological recovery, brain tissue survival and remodeling via mechanisms involving microvascular thrombosis and brain T cell infiltration. Brain Behav Immun. 2021 Jan;91:627-638. doi: 10.1016/j.bbi.2020.10.015. Epub 2020 Oct 22. PMID: 33122024.
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